STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucCsuccinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (414 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
KWZ72657.1
Citrate synthase 2; KEGG: sgt:SGGB_0689 7.6e-163 citZ; citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97.
  
 0.976
KWZ74009.1
KEGG: gva:HMPREF0424_0254 0. adh; aldehyde-alcohol dehydrogenase 2 K04072; Psort location: Cytoplasmic, score: 9.97; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.971
KWZ74068.1
Carbamoyl-phosphate synthase L chain, ATP binding domain protein; KEGG: blf:BLIF_1805 1.1e-204 propionyl-CoA carboxylase subunit alpha; K11263 acetyl-/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein; Psort location: Cytoplasmic, score: 7.50.
  
 0.955
KWZ72824.1
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate).
   
 0.948
KWZ73530.1
KEGG: bad:BAD_0992 0. pfl; formate acetyltransferase; K00656 formate C-acetyltransferase; Psort location: Cytoplasmic, score: 9.97.
     
 0.935
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.779
KWZ75216.1
KEGG: bad:BAD_0688 3.1e-173 pta; phosphate acetyltransferase; K13788 phosphate acetyltransferase; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.757
KWZ72658.1
KEGG: smn:SMA_0653 1.0e-151 icd; Isocitrate dehydrogenase [NADP]; K00031 isocitrate dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.756
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
  
 0.753
Your Current Organism:
Alloscardovia omnicolens
NCBI taxonomy Id: 419015
Other names: A. omnicolens, Alloscardovia omnicolens Huys et al. 2007, CCUG 31649, DSM 21503, LMG 23792, LMG:23792
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.