node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KWZ73524.1 | clpP | HMPREF3214_01297 | HMPREF3214_01295 | Chloride transporter, ClC family; KEGG: cpr:CPR_1400 1.3e-26 chloride channel protein K01529; Psort location: CytoplasmicMembrane, score: 10.00. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.696 |
KWZ73524.1 | clpP-2 | HMPREF3214_01297 | HMPREF3214_01296 | Chloride transporter, ClC family; KEGG: cpr:CPR_1400 1.3e-26 chloride channel protein K01529; Psort location: CytoplasmicMembrane, score: 10.00. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.703 |
KWZ73524.1 | clpX | HMPREF3214_01297 | HMPREF3214_01294 | Chloride transporter, ClC family; KEGG: cpr:CPR_1400 1.3e-26 chloride channel protein K01529; Psort location: CytoplasmicMembrane, score: 10.00. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.529 |
KWZ73524.1 | tig | HMPREF3214_01297 | HMPREF3214_01299 | Chloride transporter, ClC family; KEGG: cpr:CPR_1400 1.3e-26 chloride channel protein K01529; Psort location: CytoplasmicMembrane, score: 10.00. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.510 |
KWZ74570.1 | clpP | HMPREF3214_00683 | HMPREF3214_01295 | Negative regulator of genetic competence ClpC/MecB; KEGG: mbb:BCG_3661c 9.9e-296 clpC; putative ATP-dependent Clp protease ATP-binding subunit ClpC K03696; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.882 |
KWZ74570.1 | clpP-2 | HMPREF3214_00683 | HMPREF3214_01296 | Negative regulator of genetic competence ClpC/MecB; KEGG: mbb:BCG_3661c 9.9e-296 clpC; putative ATP-dependent Clp protease ATP-binding subunit ClpC K03696; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.882 |
KWZ74570.1 | clpX | HMPREF3214_00683 | HMPREF3214_01294 | Negative regulator of genetic competence ClpC/MecB; KEGG: mbb:BCG_3661c 9.9e-296 clpC; putative ATP-dependent Clp protease ATP-binding subunit ClpC K03696; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.437 |
KWZ74570.1 | dnaK | HMPREF3214_00683 | HMPREF3214_00251 | Negative regulator of genetic competence ClpC/MecB; KEGG: mbb:BCG_3661c 9.9e-296 clpC; putative ATP-dependent Clp protease ATP-binding subunit ClpC K03696; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.961 |
KWZ74570.1 | groS | HMPREF3214_00683 | HMPREF3214_00827 | Negative regulator of genetic competence ClpC/MecB; KEGG: mbb:BCG_3661c 9.9e-296 clpC; putative ATP-dependent Clp protease ATP-binding subunit ClpC K03696; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family. | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.691 |
atpA | clpP | HMPREF3214_00353 | HMPREF3214_01295 | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.683 |
atpA | clpP-2 | HMPREF3214_00353 | HMPREF3214_01296 | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.683 |
atpA | dnaK | HMPREF3214_00353 | HMPREF3214_00251 | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.738 |
atpA | ftsH | HMPREF3214_00353 | HMPREF3214_01695 | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.658 |
atpA | groS | HMPREF3214_00353 | HMPREF3214_00827 | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.462 |
atpA | tig | HMPREF3214_00353 | HMPREF3214_01299 | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.572 |
clpB | clpP | HMPREF3214_00266 | HMPREF3214_01295 | ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.882 |
clpB | clpP-2 | HMPREF3214_00266 | HMPREF3214_01296 | ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.882 |
clpB | clpX | HMPREF3214_00266 | HMPREF3214_01294 | ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.769 |
clpB | dnaK | HMPREF3214_00266 | HMPREF3214_00251 | ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.961 |
clpB | groS | HMPREF3214_00266 | HMPREF3214_00827 | ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.691 |