node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KWZ72834.1 | recR | HMPREF3214_01550 | HMPREF3214_01535 | KEGG: blk:BLNIAS_02588 2.6e-105 DNA polymerase III subunit delta'; K02341 DNA polymerase III subunit delta'; Psort location: Cytoplasmic, score: 9.97. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.410 |
KWZ72834.1 | tmk | HMPREF3214_01550 | HMPREF3214_01549 | KEGG: blk:BLNIAS_02588 2.6e-105 DNA polymerase III subunit delta'; K02341 DNA polymerase III subunit delta'; Psort location: Cytoplasmic, score: 9.97. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.958 |
KWZ72834.1 | topA | HMPREF3214_01550 | HMPREF3214_01548 | KEGG: blk:BLNIAS_02588 2.6e-105 DNA polymerase III subunit delta'; K02341 DNA polymerase III subunit delta'; Psort location: Cytoplasmic, score: 9.97. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.850 |
KWZ73494.1 | thyA | HMPREF3214_01266 | HMPREF3214_01495 | Haloacid dehalogenase-like hydrolase; KEGG: bni:BANAN_03975 5.9e-53 hydrolase or phosphatase; K01091 phosphoglycolate phosphatase; Psort location: Cytoplasmic, score: 7.50. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.511 |
KWZ73494.1 | tmk | HMPREF3214_01266 | HMPREF3214_01549 | Haloacid dehalogenase-like hydrolase; KEGG: bni:BANAN_03975 5.9e-53 hydrolase or phosphatase; K01091 phosphoglycolate phosphatase; Psort location: Cytoplasmic, score: 7.50. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.888 |
KWZ73991.1 | KWZ73992.1 | HMPREF3214_00831 | HMPREF3214_00832 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.999 |
KWZ73991.1 | dut | HMPREF3214_00831 | HMPREF3214_01314 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.795 |
KWZ73991.1 | thyA | HMPREF3214_00831 | HMPREF3214_01495 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.730 |
KWZ73991.1 | tmk | HMPREF3214_00831 | HMPREF3214_01549 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.955 |
KWZ73992.1 | KWZ73991.1 | HMPREF3214_00832 | HMPREF3214_00831 | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.999 |
KWZ73992.1 | tmk | HMPREF3214_00832 | HMPREF3214_01549 | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.945 |
KWZ75515.1 | dut | HMPREF3214_00379 | HMPREF3214_01314 | HAD hydrolase, family IA, variant 3; KEGG: bmq:BMQ_3994 1.2e-08 putative 5'(3')-deoxyribonucleotidase; Psort location: Cytoplasmic, score: 7.50. | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.911 |
KWZ75515.1 | tmk | HMPREF3214_00379 | HMPREF3214_01549 | HAD hydrolase, family IA, variant 3; KEGG: bmq:BMQ_3994 1.2e-08 putative 5'(3')-deoxyribonucleotidase; Psort location: Cytoplasmic, score: 7.50. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.937 |
KWZ75861.1 | tmk | HMPREF3214_00054 | HMPREF3214_01549 | Hydrolase, TatD family; KEGG: bll:BLJ_1908 3.2e-100 TatD-like deoxyribonuclease; K03424 TatD DNase family protein; Psort location: Cytoplasmic, score: 9.97. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.680 |
dut | KWZ73991.1 | HMPREF3214_01314 | HMPREF3214_00831 | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.795 |
dut | KWZ75515.1 | HMPREF3214_01314 | HMPREF3214_00379 | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | HAD hydrolase, family IA, variant 3; KEGG: bmq:BMQ_3994 1.2e-08 putative 5'(3')-deoxyribonucleotidase; Psort location: Cytoplasmic, score: 7.50. | 0.911 |
dut | thyA | HMPREF3214_01314 | HMPREF3214_01495 | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.988 |
dut | tmk | HMPREF3214_01314 | HMPREF3214_01549 | Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.956 |
recR | KWZ72834.1 | HMPREF3214_01535 | HMPREF3214_01550 | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | KEGG: blk:BLNIAS_02588 2.6e-105 DNA polymerase III subunit delta'; K02341 DNA polymerase III subunit delta'; Psort location: Cytoplasmic, score: 9.97. | 0.410 |
recR | tmk | HMPREF3214_01535 | HMPREF3214_01549 | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.874 |