STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDN65795.11-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (324 aa)    
Predicted Functional Partners:
SDN65765.1
PTS system, fructose-specific IIC component.
 
 
 0.999
SDN65823.1
Phosphocarrier protein FPr; Belongs to the PEP-utilizing enzyme family.
 
 
 0.999
SDO49346.1
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 
 0.961
pfp
Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
     
 0.947
SDO57421.1
PTS IIA-like nitrogen-regulatory protein PtsN.
 
 
 0.946
SDN70212.1
Transcriptional regulator, DeoR family.
 
  
 0.932
SDO75708.1
Transcriptional regulator, DeoR family.
 
  
 0.888
SDN65850.1
Transcriptional regulator, LacI family.
 
   
 0.817
SDO57562.1
Phosphocarrier protein NPr.
 
 
 0.749
SDN65632.1
NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family.
  
 
  0.694
Your Current Organism:
Halomonas shengliensis
NCBI taxonomy Id: 419597
Other names: CGMCC 1.6444, H. shengliensis, Halomonas shengliensis Wang et al. 2007, LMG 23897, LMG:23897, strain SL014B-85
Server load: low (18%) [HD]