node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDN69456.1 | SDN85017.1 | SAMN04487957_101412 | SAMN04487957_102171 | Homocysteine S-methyltransferase. | Homoserine dehydrogenase. | 0.751 |
SDN69456.1 | SDN92938.1 | SAMN04487957_101412 | SAMN04487957_102418 | Homocysteine S-methyltransferase. | Cystathionine gamma-synthase. | 0.631 |
SDN69456.1 | SDO07225.1 | SAMN04487957_101412 | SAMN04487957_103233 | Homocysteine S-methyltransferase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.881 |
SDN69456.1 | SDO08965.1 | SAMN04487957_101412 | SAMN04487957_103293 | Homocysteine S-methyltransferase. | O-acetylhomoserine (thiol)-lyase. | 0.736 |
SDN69456.1 | SDO65279.1 | SAMN04487957_101412 | SAMN04487957_10976 | Homocysteine S-methyltransferase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.720 |
SDN69456.1 | SDO75789.1 | SAMN04487957_101412 | SAMN04487957_11142 | Homocysteine S-methyltransferase. | GAF domain-containing protein. | 0.724 |
SDN69456.1 | luxS | SAMN04487957_101412 | SAMN04487957_103338 | Homocysteine S-methyltransferase. | S-ribosylhomocysteine lyase /quorum-sensing autoinducer 2 (AI-2) synthesis protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.747 |
SDN69456.1 | metE | SAMN04487957_101412 | SAMN04487957_10123 | Homocysteine S-methyltransferase. | Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.782 |
SDN69456.1 | metG | SAMN04487957_101412 | SAMN04487957_11610 | Homocysteine S-methyltransferase. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.856 |
SDN69456.1 | metK | SAMN04487957_101412 | SAMN04487957_10718 | Homocysteine S-methyltransferase. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.785 |
SDN85017.1 | SDN69456.1 | SAMN04487957_102171 | SAMN04487957_101412 | Homoserine dehydrogenase. | Homocysteine S-methyltransferase. | 0.751 |
SDN85017.1 | SDN92938.1 | SAMN04487957_102171 | SAMN04487957_102418 | Homoserine dehydrogenase. | Cystathionine gamma-synthase. | 0.712 |
SDN85017.1 | SDO07225.1 | SAMN04487957_102171 | SAMN04487957_103233 | Homoserine dehydrogenase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.978 |
SDN85017.1 | SDO08965.1 | SAMN04487957_102171 | SAMN04487957_103293 | Homoserine dehydrogenase. | O-acetylhomoserine (thiol)-lyase. | 0.936 |
SDN85017.1 | SDO65279.1 | SAMN04487957_102171 | SAMN04487957_10976 | Homoserine dehydrogenase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.710 |
SDN85017.1 | luxS | SAMN04487957_102171 | SAMN04487957_103338 | Homoserine dehydrogenase. | S-ribosylhomocysteine lyase /quorum-sensing autoinducer 2 (AI-2) synthesis protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.932 |
SDN85017.1 | metE | SAMN04487957_102171 | SAMN04487957_10123 | Homoserine dehydrogenase. | Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.957 |
SDN85017.1 | metG | SAMN04487957_102171 | SAMN04487957_11610 | Homoserine dehydrogenase. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.449 |
SDN85017.1 | metK | SAMN04487957_102171 | SAMN04487957_10718 | Homoserine dehydrogenase. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.425 |
SDN92938.1 | SDN69456.1 | SAMN04487957_102418 | SAMN04487957_101412 | Cystathionine gamma-synthase. | Homocysteine S-methyltransferase. | 0.631 |