node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDN70855.1 | SDO15936.1 | SAMN04487957_101457 | SAMN04487957_10480 | 6-pyruvoyl-tetrahydropterin synthase. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.506 |
SDN70855.1 | folE | SAMN04487957_101457 | SAMN04487957_105181 | 6-pyruvoyl-tetrahydropterin synthase. | GTP cyclohydrolase I. | 0.953 |
SDN83256.1 | SDO15936.1 | SAMN04487957_102100 | SAMN04487957_10480 | Dihydromonapterin reductase / dihydrofolate reductase. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.929 |
SDN83256.1 | SDO34588.1 | SAMN04487957_102100 | SAMN04487957_105250 | Dihydromonapterin reductase / dihydrofolate reductase. | Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 0.927 |
SDO15912.1 | SDO15936.1 | SAMN04487957_10479 | SAMN04487957_10480 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
SDO15912.1 | SDO34588.1 | SAMN04487957_10479 | SAMN04487957_105250 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 0.655 |
SDO15912.1 | SDO44972.1 | SAMN04487957_10479 | SAMN04487957_106172 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.995 |
SDO15912.1 | SDO45488.1 | SAMN04487957_10479 | SAMN04487957_106190 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | 0.945 |
SDO15912.1 | SDO77183.1 | SAMN04487957_10479 | SAMN04487957_11188 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | 4-amino-4-deoxychorismate lyase. | 0.449 |
SDO15912.1 | birA | SAMN04487957_10479 | SAMN04487957_11399 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.597 |
SDO15912.1 | folE | SAMN04487957_10479 | SAMN04487957_105181 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | GTP cyclohydrolase I. | 0.884 |
SDO15912.1 | plsY | SAMN04487957_10479 | SAMN04487957_10481 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | Glycerol-3-phosphate acyltransferase PlsY; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.645 |
SDO15936.1 | SDN70855.1 | SAMN04487957_10480 | SAMN04487957_101457 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 6-pyruvoyl-tetrahydropterin synthase. | 0.506 |
SDO15936.1 | SDN83256.1 | SAMN04487957_10480 | SAMN04487957_102100 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydromonapterin reductase / dihydrofolate reductase. | 0.929 |
SDO15936.1 | SDO15912.1 | SAMN04487957_10480 | SAMN04487957_10479 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | 0.999 |
SDO15936.1 | SDO34588.1 | SAMN04487957_10480 | SAMN04487957_105250 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 0.698 |
SDO15936.1 | SDO44972.1 | SAMN04487957_10480 | SAMN04487957_106172 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.994 |
SDO15936.1 | SDO45488.1 | SAMN04487957_10480 | SAMN04487957_106190 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | 0.995 |
SDO15936.1 | SDO77183.1 | SAMN04487957_10480 | SAMN04487957_11188 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 4-amino-4-deoxychorismate lyase. | 0.516 |
SDO15936.1 | birA | SAMN04487957_10480 | SAMN04487957_11399 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.561 |