STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDO88664.12-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (518 aa)    
Predicted Functional Partners:
SDO88638.1
Dihydrolipoamide dehydrogenase.
 0.999
SDO88689.1
2-oxoglutarate dehydrogenase E1 component.
 0.999
SDO90062.1
2-oxoisovalerate dehydrogenase E1 component.
 
 0.999
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.995
SDO80081.1
Dihydrolipoamide dehydrogenase.
 0.993
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.993
SDO09463.1
2-oxoisovalerate dehydrogenase E1 component beta subunit.
 0.987
SDO09489.1
2-oxoisovalerate dehydrogenase E1 component alpha subunit.
 
 0.956
SDO35294.1
glutaryl-CoA dehydrogenase.
   
  0.935
SDO30849.1
acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.929
Your Current Organism:
Halomonas shengliensis
NCBI taxonomy Id: 419597
Other names: CGMCC 1.6444, H. shengliensis, Halomonas shengliensis Wang et al. 2007, LMG 23897, LMG:23897, strain SL014B-85
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