node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDO59869.1 | SDO91146.1 | SAMN04487957_108122 | SAMN04487957_11545 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | 0.866 |
SDO59869.1 | dnaJ | SAMN04487957_108122 | SAMN04487957_106161 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.852 |
SDO59869.1 | dnaK | SAMN04487957_108122 | SAMN04487957_106160 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.979 |
SDO59869.1 | grpE | SAMN04487957_108122 | SAMN04487957_106159 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.847 |
SDO59869.1 | hslU | SAMN04487957_108122 | SAMN04487957_10283 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | ATP-dependent HslUV protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.661 |
SDO59869.1 | hslV | SAMN04487957_108122 | SAMN04487957_10282 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | ATP-dependent HslUV protease, peptidase subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.459 |
SDO59869.1 | htpG | SAMN04487957_108122 | SAMN04487957_104286 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. | 0.751 |
SDO70553.1 | SDO91146.1 | SAMN04487957_11065 | SAMN04487957_11545 | UPF0716 protein FxsA. | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | 0.600 |
SDO70553.1 | hslU | SAMN04487957_11065 | SAMN04487957_10283 | UPF0716 protein FxsA. | ATP-dependent HslUV protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.597 |
SDO70553.1 | hslV | SAMN04487957_11065 | SAMN04487957_10282 | UPF0716 protein FxsA. | ATP-dependent HslUV protease, peptidase subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.736 |
SDO91113.1 | SDO91146.1 | SAMN04487957_11544 | SAMN04487957_11545 | Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family. | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | 0.553 |
SDO91146.1 | SDO59869.1 | SAMN04487957_11545 | SAMN04487957_108122 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | 0.866 |
SDO91146.1 | SDO70553.1 | SAMN04487957_11545 | SAMN04487957_11065 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | UPF0716 protein FxsA. | 0.600 |
SDO91146.1 | SDO91113.1 | SAMN04487957_11545 | SAMN04487957_11544 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family. | 0.553 |
SDO91146.1 | clpB | SAMN04487957_11545 | SAMN04487957_1137 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.885 |
SDO91146.1 | dnaJ | SAMN04487957_11545 | SAMN04487957_106161 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.639 |
SDO91146.1 | dnaK | SAMN04487957_11545 | SAMN04487957_106160 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.775 |
SDO91146.1 | grpE | SAMN04487957_11545 | SAMN04487957_106159 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.731 |
SDO91146.1 | hslU | SAMN04487957_11545 | SAMN04487957_10283 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent HslUV protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.620 |
SDO91146.1 | hslV | SAMN04487957_11545 | SAMN04487957_10282 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent HslUV protease, peptidase subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.689 |