STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mchMethenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family. (324 aa)    
Predicted Functional Partners:
ftr
Formylmethanofuran--tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
 
 
 0.994
mtd
Methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
 
  
 0.987
Maeo_0084
Formylmethanofuran dehydrogenase; PFAM: glutamate synthase alpha subunit domain protein; molydopterin dinucleotide-binding region; KEGG: mmp:MMP0510 molybdenum containing formylmethanofuran dehydrogenase subunit C.
 
   
 0.933
hmd
Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
     
 0.922
Maeo_0034
TIGRFAM: Acetyl coenzyme A synthetase (ADP forming) alpha domain; PFAM: CoA-binding domain protein; KEGG: mja:MJ0590 hypothetical protein.
     
 0.852
Maeo_1443
PFAM: Amidohydrolase 3; KEGG: mth:MTH1557 tungsten formylmethanofuran dehydrogenase, subunit A.
 
   
 0.831
Maeo_0083
PFAM: Amidohydrolase 3; KEGG: mbu:Mbur_0284 formylmethanofuran dehydrogenase subunit A.
 
   
 0.830
Maeo_1295
PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mmp:MMP0213 triphosphoribosyl-dephospho-CoA synthetase related protein.
 
     0.830
Maeo_0244
Beta-ribofuranosylaminobenzene 5'-phosphate synthase family; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
 
   
 0.818
Maeo_1442
Formylmethanofuran dehydrogenase; PFAM: glutamate synthase alpha subunit domain protein; KEGG: mth:MTH1558 tungsten formylmethanofuran dehydrogenase, subunit C.
 
   
 0.803
Your Current Organism:
Methanococcus aeolicus
NCBI taxonomy Id: 419665
Other names: M. aeolicus Nankai-3, Methanococcus aeolicus Nankai-3, Methanococcus aeolicus str. Nankai-3, Methanococcus aeolicus strain Nankai-3
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