node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Maeo_0499 | Maeo_0910 | Maeo_0499 | Maeo_0910 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: mja:MJ0637 probable prephenate dehydratase (PDT). | PFAM: Chorismate mutase; KEGG: mja:MJ0246 chorismate mutase. | 0.971 |
Maeo_0499 | Maeo_1024 | Maeo_0499 | Maeo_1024 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: mja:MJ0637 probable prephenate dehydratase (PDT). | PFAM: Prephenate dehydrogenase; KEGG: mja:MJ0612 prephenate dehydrogenase. | 0.984 |
Maeo_0499 | Maeo_1192 | Maeo_0499 | Maeo_1192 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: mja:MJ0637 probable prephenate dehydratase (PDT). | PFAM: aminotransferase class I and II; KEGG: mja:MJ0001 putative aspartate aminotransferase 1 (transaminase A) (ASPAT). | 0.990 |
Maeo_0499 | aroA | Maeo_0499 | Maeo_0149 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: mja:MJ0637 probable prephenate dehydratase (PDT). | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.811 |
Maeo_0499 | aroC | Maeo_0499 | Maeo_0689 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: mja:MJ0637 probable prephenate dehydratase (PDT). | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.764 |
Maeo_0499 | aroE | Maeo_0499 | Maeo_0450 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: mja:MJ0637 probable prephenate dehydratase (PDT). | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.492 |
Maeo_0499 | hisC | Maeo_0499 | Maeo_0250 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: mja:MJ0637 probable prephenate dehydratase (PDT). | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: mmp:MMP1216 histidinol-phosphate aminotransferase. | 0.968 |
Maeo_0499 | hisG | Maeo_0499 | Maeo_0137 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: mja:MJ0637 probable prephenate dehydratase (PDT). | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.510 |
Maeo_0910 | Maeo_0499 | Maeo_0910 | Maeo_0499 | PFAM: Chorismate mutase; KEGG: mja:MJ0246 chorismate mutase. | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: mja:MJ0637 probable prephenate dehydratase (PDT). | 0.971 |
Maeo_0910 | Maeo_1024 | Maeo_0910 | Maeo_1024 | PFAM: Chorismate mutase; KEGG: mja:MJ0246 chorismate mutase. | PFAM: Prephenate dehydrogenase; KEGG: mja:MJ0612 prephenate dehydrogenase. | 0.980 |
Maeo_0910 | aroA | Maeo_0910 | Maeo_0149 | PFAM: Chorismate mutase; KEGG: mja:MJ0246 chorismate mutase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.942 |
Maeo_0910 | aroC | Maeo_0910 | Maeo_0689 | PFAM: Chorismate mutase; KEGG: mja:MJ0246 chorismate mutase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.991 |
Maeo_0910 | aroD | Maeo_0910 | Maeo_0132 | PFAM: Chorismate mutase; KEGG: mja:MJ0246 chorismate mutase. | 3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.626 |
Maeo_0910 | aroE | Maeo_0910 | Maeo_0450 | PFAM: Chorismate mutase; KEGG: mja:MJ0246 chorismate mutase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.626 |
Maeo_0910 | hisC | Maeo_0910 | Maeo_0250 | PFAM: Chorismate mutase; KEGG: mja:MJ0246 chorismate mutase. | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: mmp:MMP1216 histidinol-phosphate aminotransferase. | 0.738 |
Maeo_0910 | hisG | Maeo_0910 | Maeo_0137 | PFAM: Chorismate mutase; KEGG: mja:MJ0246 chorismate mutase. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.497 |
Maeo_1024 | Maeo_0499 | Maeo_1024 | Maeo_0499 | PFAM: Prephenate dehydrogenase; KEGG: mja:MJ0612 prephenate dehydrogenase. | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: mja:MJ0637 probable prephenate dehydratase (PDT). | 0.984 |
Maeo_1024 | Maeo_0910 | Maeo_1024 | Maeo_0910 | PFAM: Prephenate dehydrogenase; KEGG: mja:MJ0612 prephenate dehydrogenase. | PFAM: Chorismate mutase; KEGG: mja:MJ0246 chorismate mutase. | 0.980 |
Maeo_1024 | Maeo_1192 | Maeo_1024 | Maeo_1192 | PFAM: Prephenate dehydrogenase; KEGG: mja:MJ0612 prephenate dehydrogenase. | PFAM: aminotransferase class I and II; KEGG: mja:MJ0001 putative aspartate aminotransferase 1 (transaminase A) (ASPAT). | 0.942 |
Maeo_1024 | aroA | Maeo_1024 | Maeo_0149 | PFAM: Prephenate dehydrogenase; KEGG: mja:MJ0612 prephenate dehydrogenase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.653 |