STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Maeo_1133PFAM: protein of unknown function DUF87; KEGG: mja:MJ1565 hypothetical protein. (496 aa)    
Predicted Functional Partners:
Maeo_0018
KEGG: mmp:MMP1209 hypothetical protein.
   
 
 0.890
gatE
Putative aspartyl-tRNA(Asn) amidotransferase, B subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
 
     0.758
rad50
SMC domain protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily.
 
   
 0.682
mre11
Metallophosphoesterase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family.
 
   
 0.665
Maeo_1131
PFAM: Sjogrens syndrome scleroderma autoantigen 1; KEGG: mmp:MMP0134 hypothetical protein.
       0.473
Maeo_0920
AAA family ATPase, CDC48 subfamily; KEGG: mmp:MMP0176 CDC48 cell division cycle protein family member; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein; AAA ATPase central domain protein; cell division protein 48 CDC48 domain 2; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase.
 
   
 0.406
Your Current Organism:
Methanococcus aeolicus
NCBI taxonomy Id: 419665
Other names: M. aeolicus Nankai-3, Methanococcus aeolicus Nankai-3, Methanococcus aeolicus str. Nankai-3, Methanococcus aeolicus strain Nankai-3
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