| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OJG87856.1 | OJG90772.1 | RV16_GL000581 | RV16_GL001020 | Hypothetical protein. | L-serine dehydratase, iron-sulfur-dependent, beta subunit. | 0.804 |
| OJG87856.1 | OJG90773.1 | RV16_GL000581 | RV16_GL001021 | Hypothetical protein. | L-serine dehydratase, iron-sulfur-dependent, alpha subunit. | 0.804 |
| OJG87856.1 | OJG91143.1 | RV16_GL000581 | RV16_GL000129 | Hypothetical protein. | Serine O-acetyltransferase. | 0.834 |
| OJG87856.1 | ilvA | RV16_GL000581 | RV16_GL000932 | Hypothetical protein. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.465 |
| OJG87856.1 | metAA | RV16_GL000581 | RV16_GL000578 | Hypothetical protein. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.970 |
| OJG87856.1 | thrB | RV16_GL000581 | RV16_GL000580 | Hypothetical protein. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.999 |
| OJG90357.1 | OJG90772.1 | RV16_GL001758 | RV16_GL001020 | Hypothetical protein. | L-serine dehydratase, iron-sulfur-dependent, beta subunit. | 0.901 |
| OJG90357.1 | OJG90773.1 | RV16_GL001758 | RV16_GL001021 | Hypothetical protein. | L-serine dehydratase, iron-sulfur-dependent, alpha subunit. | 0.903 |
| OJG90357.1 | OJG91143.1 | RV16_GL001758 | RV16_GL000129 | Hypothetical protein. | Serine O-acetyltransferase. | 0.800 |
| OJG90357.1 | glyA | RV16_GL001758 | RV16_GL000965 | Hypothetical protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.909 |
| OJG90357.1 | ilvA | RV16_GL001758 | RV16_GL000932 | Hypothetical protein. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.904 |
| OJG90357.1 | metAA | RV16_GL001758 | RV16_GL000578 | Hypothetical protein. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.837 |
| OJG90357.1 | trpA | RV16_GL001758 | RV16_GL000927 | Hypothetical protein. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.900 |
| OJG90357.1 | trpB | RV16_GL001758 | RV16_GL000926 | Hypothetical protein. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
| OJG90772.1 | OJG87856.1 | RV16_GL001020 | RV16_GL000581 | L-serine dehydratase, iron-sulfur-dependent, beta subunit. | Hypothetical protein. | 0.804 |
| OJG90772.1 | OJG90357.1 | RV16_GL001020 | RV16_GL001758 | L-serine dehydratase, iron-sulfur-dependent, beta subunit. | Hypothetical protein. | 0.901 |
| OJG90772.1 | OJG90773.1 | RV16_GL001020 | RV16_GL001021 | L-serine dehydratase, iron-sulfur-dependent, beta subunit. | L-serine dehydratase, iron-sulfur-dependent, alpha subunit. | 0.999 |
| OJG90772.1 | OJG91143.1 | RV16_GL001020 | RV16_GL000129 | L-serine dehydratase, iron-sulfur-dependent, beta subunit. | Serine O-acetyltransferase. | 0.905 |
| OJG90772.1 | glyA | RV16_GL001020 | RV16_GL000965 | L-serine dehydratase, iron-sulfur-dependent, beta subunit. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.961 |
| OJG90772.1 | ilvA | RV16_GL001020 | RV16_GL000932 | L-serine dehydratase, iron-sulfur-dependent, beta subunit. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.936 |
