Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
xseAExodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (442 aa)    
Predicted Functional Partners:
xseB
Hypothetical protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
  
 0.999
OJG90847.1
Hypothetical protein; Belongs to the FPP/GGPP synthase family.
 
  
 0.931
folD
FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
    0.916
OJG90850.1
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
   
 0.902
OJG90291.1
single-stranded-DNA-specific exonuclease RecJ.
  
  
 0.812
OJG90848.1
Hemolysin A.
  
    0.791
nusB
Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
  
    0.737
argR-2
Arginine repressor; Regulates arginine biosynthesis genes.
       0.690
OJG90842.1
Hypothetical protein.
       0.687
ruvB
Holliday junction ATP-dependent DNA helicase ruvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
 
   
 0.615
Your Current Organism:
Enterococcus saccharolyticus
NCBI taxonomy Id: 41997
Other names: ATCC 43076, CCUG 27643, CCUG 33311, CIP 103246, DSM 20726, E. saccharolyticus, JCM 8734, LMG 11427, LMG:11427, NBRC 100493, NCDO 2594, NCIMB 702594, Streptococcus saccharolyticus
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