STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Msm_0788Aspartate aminotransferase; COG0436. (370 aa)    
Predicted Functional Partners:
Msm_1052
Prephenate dehydratase, PheA; COG0077.
 
 
 0.991
Msm_0160
Asparagine synthetase, AsnB; COG0367.
 
 
 0.960
hisC
Histidinol-phosphate aminotransferase, HisC; COG0079.
 
 
0.938
Msm_0500
N-carbamoyl-D-amino acid amidohydrolase; COG0388.
  
 
 0.935
argG
Argininosuccinate synthase, ArgG; COG0137; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 0.935
purA
Adenylosuccinate synthetase, PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 0.927
Msm_0888
Glutamate dehydrogenase (NADP+), GdhA; COG0334; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.925
Msm_0271
Cysteine synthase, CysK; COG0031.
  
 0.924
mfnA
Tyrosine decarboxylase, MfnA; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.
  
 
 0.924
Msm_0641
Prephenate dehydrogenase (NADP+); COG0287.
    
 0.923
Your Current Organism:
Methanobrevibacter smithii
NCBI taxonomy Id: 420247
Other names: M. smithii ATCC 35061, Methanobrevibacter smithii ATCC 35061, Methanobrevibacter smithii DSM 861, Methanobrevibacter smithii PS, Methanobrevibacter smithii str. ATCC 35061, Methanobrevibacter smithii strain ATCC 35061
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