Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msm_0803Predicted metal-dependent membrane protease, CAAX amino terminal protease family; COG1266. (221 aa)    
Predicted Functional Partners:
Msm_0480
YcaO-like protein; COG1944.
  
  
 0.627
Msm_1484
Multidrug ABC transporter, permease component; COG0842.
 
  
 0.568
Msm_0804
Translation initiation factor aIF-2B, alpha subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
  
    0.518
Msm_1248
Multidrug ABC transporter, permease component; COG0842.
  
  
 0.489
Msm_1722
Nitroreductase; COG0778.
 
  
 0.473
Msm_1574
Nitroreductase, NfnB; COG0778.
 
  
 0.470
Msm_1293
Nitroreductase, NADH oxidase/flavin reductase family; COG0778.
 
  
 0.463
Msm_1180
Predicted metal-dependent membrane protease; COG1266.
  
     0.459
Your Current Organism:
Methanobrevibacter smithii
NCBI taxonomy Id: 420247
Other names: M. smithii ATCC 35061, Methanobrevibacter smithii ATCC 35061, Methanobrevibacter smithii DSM 861, Methanobrevibacter smithii PS, Methanobrevibacter smithii str. ATCC 35061, Methanobrevibacter smithii strain ATCC 35061
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