Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msm_0806Polar amino acid ABC transporter, permease component; COG0765. (216 aa)    
Predicted Functional Partners:
Msm_0807
Polar amino acid ABC transporter, substrate-binding component.
 0.999
Msm_0805
Polar amino acid ABC transporter, ATPase component; COG1126.
 
 0.998
Msm_0953
Conserved hypothetical membrane protein Msm_0953.
  
  
 0.553
argG
Argininosuccinate synthase, ArgG; COG0137; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
  
 0.487
Msm_0991
Nitrate/sulfonate/bicarbonate ABC transporter, substrate-binding component; COG1174.
    
 0.474
argH
Argininosuccinate lyase, ArgH; COG0165.
  
  
 0.473
Msm_0808
Nitrogenase iron-molybdenum cofactor biosynthesis protein, NifB; COG0535.
     
 0.464
ecfA-2
Cobalt ABC transporter, ATPase component, CbiO; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
 0.450
ecfA
Cobalt ABC transporter, ATPase component, CbiO; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
 0.445
Msm_0271
Cysteine synthase, CysK; COG0031.
  
  
 0.436
Your Current Organism:
Methanobrevibacter smithii
NCBI taxonomy Id: 420247
Other names: M. smithii ATCC 35061, Methanobrevibacter smithii ATCC 35061, Methanobrevibacter smithii DSM 861, Methanobrevibacter smithii PS, Methanobrevibacter smithii str. ATCC 35061, Methanobrevibacter smithii strain ATCC 35061
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