node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEH43899.1 | SEH51830.1 | SAMN05421793_10446 | SAMN05421793_10916 | 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase). | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | 0.712 |
SEH43899.1 | SEH51846.1 | SAMN05421793_10446 | SAMN05421793_10917 | 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase). | Succinate dehydrogenase subunit A. | 0.634 |
SEH43899.1 | SEH55238.1 | SAMN05421793_10446 | SAMN05421793_11131 | 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase). | Glutamate synthase (NADPH/NADH) large chain. | 0.867 |
SEH43899.1 | SEH71979.1 | SAMN05421793_10446 | SAMN05421793_1232 | 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase). | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | 0.902 |
SEH43899.1 | SEH81612.1 | SAMN05421793_10446 | SAMN05421793_13415 | 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase). | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.956 |
SEH43899.1 | SEH82660.1 | SAMN05421793_10446 | SAMN05421793_1361 | 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase). | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.729 |
SEH43899.1 | sucC | SAMN05421793_10446 | SAMN05421793_10673 | 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase). | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.970 |
SEH43899.1 | sucD | SAMN05421793_10446 | SAMN05421793_11142 | 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase). | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.965 |
SEH51830.1 | SEH43899.1 | SAMN05421793_10916 | SAMN05421793_10446 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase). | 0.712 |
SEH51830.1 | SEH51846.1 | SAMN05421793_10916 | SAMN05421793_10917 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | Succinate dehydrogenase subunit A. | 0.999 |
SEH51830.1 | SEH71979.1 | SAMN05421793_10916 | SAMN05421793_1232 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | 0.721 |
SEH51830.1 | SEH75570.1 | SAMN05421793_10916 | SAMN05421793_12619 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | 0.712 |
SEH51830.1 | SEH76124.1 | SAMN05421793_10916 | SAMN05421793_1276 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | Malate synthase; Belongs to the malate synthase family. | 0.467 |
SEH51830.1 | SEH81612.1 | SAMN05421793_10916 | SAMN05421793_13415 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.712 |
SEH51830.1 | SEH82660.1 | SAMN05421793_10916 | SAMN05421793_1361 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.610 |
SEH51830.1 | sucC | SAMN05421793_10916 | SAMN05421793_10673 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.975 |
SEH51830.1 | sucD | SAMN05421793_10916 | SAMN05421793_11142 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.981 |
SEH51846.1 | SEH43899.1 | SAMN05421793_10917 | SAMN05421793_10446 | Succinate dehydrogenase subunit A. | 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase). | 0.634 |
SEH51846.1 | SEH51830.1 | SAMN05421793_10917 | SAMN05421793_10916 | Succinate dehydrogenase subunit A. | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | 0.999 |
SEH51846.1 | SEH55238.1 | SAMN05421793_10917 | SAMN05421793_11131 | Succinate dehydrogenase subunit A. | Glutamate synthase (NADPH/NADH) large chain. | 0.461 |