node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEH44353.1 | SEH62424.1 | SAMN05421793_10485 | SAMN05421793_1162 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | DnaJ domain-containing protein. | 0.417 |
SEH44353.1 | SEH62564.1 | SAMN05421793_10485 | SAMN05421793_11611 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Curved DNA-binding protein. | 0.442 |
SEH44353.1 | SEH71960.1 | SAMN05421793_10485 | SAMN05421793_1231 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone HtpG. | 0.650 |
SEH44353.1 | SEH72080.1 | SAMN05421793_10485 | SAMN05421793_1238 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.774 |
SEH44353.1 | dnaK | SAMN05421793_10485 | SAMN05421793_14816 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.696 |
SEH44353.1 | grpE | SAMN05421793_10485 | SAMN05421793_14712 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.570 |
SEH44353.1 | lon | SAMN05421793_10485 | SAMN05421793_1032 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.481 |
SEH62424.1 | SEH44353.1 | SAMN05421793_1162 | SAMN05421793_10485 | DnaJ domain-containing protein. | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | 0.417 |
SEH62424.1 | SEH71960.1 | SAMN05421793_1162 | SAMN05421793_1231 | DnaJ domain-containing protein. | Molecular chaperone HtpG. | 0.958 |
SEH62424.1 | SEH72080.1 | SAMN05421793_1162 | SAMN05421793_1238 | DnaJ domain-containing protein. | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.603 |
SEH62424.1 | clpP | SAMN05421793_1162 | SAMN05421793_12525 | DnaJ domain-containing protein. | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.463 |
SEH62424.1 | dnaK | SAMN05421793_1162 | SAMN05421793_14816 | DnaJ domain-containing protein. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.981 |
SEH62424.1 | groS | SAMN05421793_1162 | SAMN05421793_1015 | DnaJ domain-containing protein. | Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.490 |
SEH62424.1 | grpE | SAMN05421793_1162 | SAMN05421793_14712 | DnaJ domain-containing protein. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.761 |
SEH62424.1 | lon | SAMN05421793_1162 | SAMN05421793_1032 | DnaJ domain-containing protein. | ATP-dependent Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.411 |
SEH62564.1 | SEH44353.1 | SAMN05421793_11611 | SAMN05421793_10485 | Curved DNA-binding protein. | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | 0.442 |
SEH62564.1 | SEH71960.1 | SAMN05421793_11611 | SAMN05421793_1231 | Curved DNA-binding protein. | Molecular chaperone HtpG. | 0.953 |
SEH62564.1 | SEH72080.1 | SAMN05421793_11611 | SAMN05421793_1238 | Curved DNA-binding protein. | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.607 |
SEH62564.1 | clpP | SAMN05421793_11611 | SAMN05421793_12525 | Curved DNA-binding protein. | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.463 |
SEH62564.1 | dnaK | SAMN05421793_11611 | SAMN05421793_14816 | Curved DNA-binding protein. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.997 |