node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mpe_A0272 | rlmD | Mpe_A0272 | Mpe_A1256 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Putative 23S rRNA (uracil-5-)-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.499 |
Mpe_A0272 | trmB | Mpe_A0272 | Mpe_A2850 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.469 |
Mpe_A1254 | pcm | Mpe_A1254 | Mpe_A1253 | Subfamily M23B unassigned peptidase. | L-isoaspartate(D-aspartate) O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. | 0.840 |
Mpe_A1254 | rlmD | Mpe_A1254 | Mpe_A1256 | Subfamily M23B unassigned peptidase. | Putative 23S rRNA (uracil-5-)-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.628 |
Mpe_A1254 | rpoS | Mpe_A1254 | Mpe_A1255 | Subfamily M23B unassigned peptidase. | RNA polymerase sigma S (sigma-38) factor transcription regulator protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. | 0.828 |
Mpe_A1254 | surE | Mpe_A1254 | Mpe_A1252 | Subfamily M23B unassigned peptidase. | Exopolyphosphatase / 3'-nucleotidase / 5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.849 |
Mpe_A1965 | rlmD | Mpe_A1965 | Mpe_A1256 | Putative tRNA/rRNA methyltransferase protein. | Putative 23S rRNA (uracil-5-)-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.551 |
guaA | lysS | Mpe_A1622 | Mpe_A0600 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.957 |
guaA | rlmD | Mpe_A1622 | Mpe_A1256 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Putative 23S rRNA (uracil-5-)-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.529 |
guaA | rpoS | Mpe_A1622 | Mpe_A1255 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | RNA polymerase sigma S (sigma-38) factor transcription regulator protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. | 0.534 |
guaA | surE | Mpe_A1622 | Mpe_A1252 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Exopolyphosphatase / 3'-nucleotidase / 5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.951 |
guaA | trmB | Mpe_A1622 | Mpe_A2850 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.422 |
lysS | guaA | Mpe_A0600 | Mpe_A1622 | lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.957 |
lysS | rlmD | Mpe_A0600 | Mpe_A1256 | lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. | Putative 23S rRNA (uracil-5-)-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.643 |
lysS | rpoS | Mpe_A0600 | Mpe_A1255 | lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. | RNA polymerase sigma S (sigma-38) factor transcription regulator protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. | 0.415 |
pcm | Mpe_A1254 | Mpe_A1253 | Mpe_A1254 | L-isoaspartate(D-aspartate) O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. | Subfamily M23B unassigned peptidase. | 0.840 |
pcm | rlmD | Mpe_A1253 | Mpe_A1256 | L-isoaspartate(D-aspartate) O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. | Putative 23S rRNA (uracil-5-)-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.628 |
pcm | rpoS | Mpe_A1253 | Mpe_A1255 | L-isoaspartate(D-aspartate) O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. | RNA polymerase sigma S (sigma-38) factor transcription regulator protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. | 0.806 |
pcm | surE | Mpe_A1253 | Mpe_A1252 | L-isoaspartate(D-aspartate) O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. | Exopolyphosphatase / 3'-nucleotidase / 5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.949 |
rlmB | rlmD | Mpe_A1817 | Mpe_A1256 | Putative tRNA/rRNA methyltransferase protein; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | Putative 23S rRNA (uracil-5-)-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.466 |