STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
truAPseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (260 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.895
rplQ
LSU ribosomal protein L17P.
  
  
 0.863
trpF
Phosphoribosylanthranilate isomerase; Belongs to the TrpF family.
     
 0.861
trpA
Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.830
trpB
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.822
Mpe_A2160
Putative transmembrane protein.
  
  
 0.818
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
  
 0.794
truB
Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
 
 0.726
cbiQ
ABC type permease; Co transport.
  
  
 0.689
Mpe_A2154
Bifunctional protein: folylpolyglutamate synthase and dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family.
 
   
 0.663
Your Current Organism:
Methylibium petroleiphilum
NCBI taxonomy Id: 420662
Other names: M. petroleiphilum PM1, MTBE-degrading bacterium PM1, Methylibium petroleiphilum PM1, Methylibium petroleiphilum str. PM1, Methylibium petroleiphilum strain PM1, Rubrivivax gelatinosus PM1
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