node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mpe_A0338 | Mpe_A2257 | Mpe_A0338 | Mpe_A2257 | NADH dehydrogenase (quinone). | Putative ferredoxin (2Fe-2S) protein. | 0.827 |
Mpe_A0338 | Mpe_A3102 | Mpe_A0338 | Mpe_A3102 | NADH dehydrogenase (quinone). | Glutamate synthase (NADH) small subunit. | 0.694 |
Mpe_A2257 | Mpe_A0338 | Mpe_A2257 | Mpe_A0338 | Putative ferredoxin (2Fe-2S) protein. | NADH dehydrogenase (quinone). | 0.827 |
Mpe_A2257 | Mpe_A2260 | Mpe_A2257 | Mpe_A2260 | Putative ferredoxin (2Fe-2S) protein. | Conserved hypothetical protein; Belongs to the HesB/IscA family. | 0.944 |
Mpe_A2257 | Mpe_A2261 | Mpe_A2257 | Mpe_A2261 | Putative ferredoxin (2Fe-2S) protein. | (Fe-S) cluster formation/repair protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.991 |
Mpe_A2257 | Mpe_A2263 | Mpe_A2257 | Mpe_A2263 | Putative ferredoxin (2Fe-2S) protein. | Transcriptional regulator, BadM/Rrf2 family. | 0.706 |
Mpe_A2257 | Mpe_A3102 | Mpe_A2257 | Mpe_A3102 | Putative ferredoxin (2Fe-2S) protein. | Glutamate synthase (NADH) small subunit. | 0.612 |
Mpe_A2257 | cyaY | Mpe_A2257 | Mpe_A3115 | Putative ferredoxin (2Fe-2S) protein. | CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.856 |
Mpe_A2257 | dnaQ | Mpe_A2257 | Mpe_A2256 | Putative ferredoxin (2Fe-2S) protein. | DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.602 |
Mpe_A2257 | hscA | Mpe_A2257 | Mpe_A2258 | Putative ferredoxin (2Fe-2S) protein. | Chaperone protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.972 |
Mpe_A2257 | hscB | Mpe_A2257 | Mpe_A2259 | Putative ferredoxin (2Fe-2S) protein. | Chaperone protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.993 |
Mpe_A2257 | iscS | Mpe_A2257 | Mpe_A2262 | Putative ferredoxin (2Fe-2S) protein. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.977 |
Mpe_A2260 | Mpe_A2257 | Mpe_A2260 | Mpe_A2257 | Conserved hypothetical protein; Belongs to the HesB/IscA family. | Putative ferredoxin (2Fe-2S) protein. | 0.944 |
Mpe_A2260 | Mpe_A2261 | Mpe_A2260 | Mpe_A2261 | Conserved hypothetical protein; Belongs to the HesB/IscA family. | (Fe-S) cluster formation/repair protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.988 |
Mpe_A2260 | Mpe_A2263 | Mpe_A2260 | Mpe_A2263 | Conserved hypothetical protein; Belongs to the HesB/IscA family. | Transcriptional regulator, BadM/Rrf2 family. | 0.838 |
Mpe_A2260 | cyaY | Mpe_A2260 | Mpe_A3115 | Conserved hypothetical protein; Belongs to the HesB/IscA family. | CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.449 |
Mpe_A2260 | dnaQ | Mpe_A2260 | Mpe_A2256 | Conserved hypothetical protein; Belongs to the HesB/IscA family. | DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.456 |
Mpe_A2260 | hscA | Mpe_A2260 | Mpe_A2258 | Conserved hypothetical protein; Belongs to the HesB/IscA family. | Chaperone protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.879 |
Mpe_A2260 | hscB | Mpe_A2260 | Mpe_A2259 | Conserved hypothetical protein; Belongs to the HesB/IscA family. | Chaperone protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.984 |
Mpe_A2260 | iscS | Mpe_A2260 | Mpe_A2262 | Conserved hypothetical protein; Belongs to the HesB/IscA family. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.970 |