| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Mpe_A0159 | Mpe_A2165 | Mpe_A0159 | Mpe_A2165 | Malate synthase; Belongs to the malate synthase family. | Citrate synthase; Belongs to the citrate synthase family. | 0.968 |
| Mpe_A0159 | Mpe_A3255 | Mpe_A0159 | Mpe_A3255 | Malate synthase; Belongs to the malate synthase family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.834 |
| Mpe_A0159 | mdh | Mpe_A0159 | Mpe_A2172 | Malate synthase; Belongs to the malate synthase family. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.939 |
| Mpe_A0159 | pckG | Mpe_A0159 | Mpe_A3705 | Malate synthase; Belongs to the malate synthase family. | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.841 |
| Mpe_A0159 | ppc | Mpe_A0159 | Mpe_A3003 | Malate synthase; Belongs to the malate synthase family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. | 0.834 |
| Mpe_A1521 | Mpe_A3255 | Mpe_A1521 | Mpe_A3255 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.917 |
| Mpe_A1521 | eno | Mpe_A1521 | Mpe_A2847 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.934 |
| Mpe_A1521 | pckG | Mpe_A1521 | Mpe_A3705 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.921 |
| Mpe_A1521 | ppc | Mpe_A1521 | Mpe_A3003 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. | 0.917 |
| Mpe_A1521 | pykF | Mpe_A1521 | Mpe_A0290 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.930 |
| Mpe_A2165 | Mpe_A0159 | Mpe_A2165 | Mpe_A0159 | Citrate synthase; Belongs to the citrate synthase family. | Malate synthase; Belongs to the malate synthase family. | 0.968 |
| Mpe_A2165 | Mpe_A3255 | Mpe_A2165 | Mpe_A3255 | Citrate synthase; Belongs to the citrate synthase family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.834 |
| Mpe_A2165 | eno | Mpe_A2165 | Mpe_A2847 | Citrate synthase; Belongs to the citrate synthase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.509 |
| Mpe_A2165 | mdh | Mpe_A2165 | Mpe_A2172 | Citrate synthase; Belongs to the citrate synthase family. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.994 |
| Mpe_A2165 | pckG | Mpe_A2165 | Mpe_A3705 | Citrate synthase; Belongs to the citrate synthase family. | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.931 |
| Mpe_A2165 | ppc | Mpe_A2165 | Mpe_A3003 | Citrate synthase; Belongs to the citrate synthase family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. | 0.834 |
| Mpe_A2165 | pykF | Mpe_A2165 | Mpe_A0290 | Citrate synthase; Belongs to the citrate synthase family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.445 |
| Mpe_A3255 | Mpe_A0159 | Mpe_A3255 | Mpe_A0159 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | Malate synthase; Belongs to the malate synthase family. | 0.834 |
| Mpe_A3255 | Mpe_A1521 | Mpe_A3255 | Mpe_A1521 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.917 |
| Mpe_A3255 | Mpe_A2165 | Mpe_A3255 | Mpe_A2165 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | Citrate synthase; Belongs to the citrate synthase family. | 0.834 |