BK809_0006519 protein (Diplodia seriata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

BK809_0006519

Uncharacterized protein. (714 aa)

Predicted Functional Partners:

BK809_0004920

0.819

BK809_0006405

0.742

BK809_0006514

0.742

BK809_0003816

0.588

BK809_0004269

0.583

BK809_0002267

0.583

BK809_0001005

0.582

BK809_0001371

0.582

BK809_0003185

0.582

BK809_0000951

0.581

Your Current Organism:

Diplodia seriata

NCBI taxonomy Id: 420778
Other names: Botryosphaeria obtusa, CBS 112555, D. seriata

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structured XML interaction data, according to the 'PSI-MI' data standard

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BK809_0000951	BK809_0001005	A0A1S8B6E0	A0A1S8B5L5	37S ribosomal protein S9, mitochondrial.	30S ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family.	0.999
BK809_0000951	BK809_0001371	A0A1S8B6E0	A0A1S8B8X1	37S ribosomal protein S9, mitochondrial.	Ribosomal protein S16, mitochondrial.	0.999
BK809_0000951	BK809_0002267	A0A1S8B6E0	A0A1S8BF26	37S ribosomal protein S9, mitochondrial.	37S ribosomal protein mrp4, mitochondrial.	0.999
BK809_0000951	BK809_0003185	A0A1S8B6E0	A0A1S8BMG0	37S ribosomal protein S9, mitochondrial.	Uncharacterized protein.	0.999
BK809_0000951	BK809_0006519	A0A1S8B6E0	A0A1S8B408	37S ribosomal protein S9, mitochondrial.	Uncharacterized protein.	0.581
BK809_0001005	BK809_0000951	A0A1S8B5L5	A0A1S8B6E0	30S ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family.	37S ribosomal protein S9, mitochondrial.	0.999
BK809_0001005	BK809_0001371	A0A1S8B5L5	A0A1S8B8X1	30S ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family.	Ribosomal protein S16, mitochondrial.	0.999
BK809_0001005	BK809_0002267	A0A1S8B5L5	A0A1S8BF26	30S ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family.	37S ribosomal protein mrp4, mitochondrial.	0.999
BK809_0001005	BK809_0003185	A0A1S8B5L5	A0A1S8BMG0	30S ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family.	Uncharacterized protein.	0.999
BK809_0001005	BK809_0006519	A0A1S8B5L5	A0A1S8B408	30S ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family.	Uncharacterized protein.	0.582
BK809_0001371	BK809_0000951	A0A1S8B8X1	A0A1S8B6E0	Ribosomal protein S16, mitochondrial.	37S ribosomal protein S9, mitochondrial.	0.999
BK809_0001371	BK809_0001005	A0A1S8B8X1	A0A1S8B5L5	Ribosomal protein S16, mitochondrial.	30S ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family.	0.999
BK809_0001371	BK809_0002267	A0A1S8B8X1	A0A1S8BF26	Ribosomal protein S16, mitochondrial.	37S ribosomal protein mrp4, mitochondrial.	0.999
BK809_0001371	BK809_0003185	A0A1S8B8X1	A0A1S8BMG0	Ribosomal protein S16, mitochondrial.	Uncharacterized protein.	0.999
BK809_0001371	BK809_0006519	A0A1S8B8X1	A0A1S8B408	Ribosomal protein S16, mitochondrial.	Uncharacterized protein.	0.582
BK809_0002267	BK809_0000951	A0A1S8BF26	A0A1S8B6E0	37S ribosomal protein mrp4, mitochondrial.	37S ribosomal protein S9, mitochondrial.	0.999
BK809_0002267	BK809_0001005	A0A1S8BF26	A0A1S8B5L5	37S ribosomal protein mrp4, mitochondrial.	30S ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family.	0.999
BK809_0002267	BK809_0001371	A0A1S8BF26	A0A1S8B8X1	37S ribosomal protein mrp4, mitochondrial.	Ribosomal protein S16, mitochondrial.	0.999
BK809_0002267	BK809_0003185	A0A1S8BF26	A0A1S8BMG0	37S ribosomal protein mrp4, mitochondrial.	Uncharacterized protein.	0.999
BK809_0002267	BK809_0006519	A0A1S8BF26	A0A1S8B408	37S ribosomal protein mrp4, mitochondrial.	Uncharacterized protein.	0.583

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

41

average node degree:

7.45

avg. local clustering coefficient:

0.924

expected number of edges:

11

PPI enrichment p-value:

1.11e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042819

Vitamin B6 biosynthetic process

6 of 10

2.44

4.82

2.42e-10

GO:0042823

Pyridoxal phosphate biosynthetic process

5 of 6

2.59

4.39

3.76e-09

GO:0008615

Pyridoxine biosynthetic process

5 of 9

2.41

4.14

6.41e-09

GO:1901617

Organic hydroxy compound biosynthetic process

6 of 30

1.97

3.54

6.41e-09

GO:0019438

Aromatic compound biosynthetic process

7 of 258

1.1

1.17

2.47e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0050570

4-hydroxythreonine-4-phosphate dehydrogenase activity

3 of 3

2.66

2.09

0.00014

GO:0050897

Cobalt ion binding

3 of 6

2.36

1.87

0.00030

GO:0000287

Magnesium ion binding

5 of 105

1.34

1.22

0.00056

GO:0051287

NAD binding

3 of 49

1.45

0.78

0.0211

GO:0046872

Metal ion binding

7 of 610

0.72

0.47

0.0174

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005622

Intracellular anatomical structure

11 of 1859

0.44

0.35

0.0027

GO:0005737

Cytoplasm

10 of 1759

0.42

0.31

0.0159

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:575

Mixed, incl. mRNA processing, and K Homology domain, type 2

5 of 5

2.66

4.4

4.56e-09

CL:7368

Pyridoxal phosphate biosynthetic process, and Glycine zipper 2TM domain

2 of 5

2.27

0.8

0.0332

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00750

Vitamin B6 metabolism

6 of 17

2.21

4.5

2.45e-10

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0664

Pyridoxine biosynthesis

3 of 6

2.36

2.01

0.00016

KW-0460

Magnesium

4 of 151

1.09

0.66

0.0192

KW-0520

NAD

3 of 74

1.27

0.66

0.0315

KW-0963

Cytoplasm

6 of 393

0.85

0.58

0.0092

KW-0560

Oxidoreductase

4 of 222

0.92

0.5

0.0406

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF04166

Pyridoxal phosphate biosynthetic protein PdxA

3 of 3

2.66

2.13

0.00012

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR005255

PdxA family

3 of 3

2.66

1.91

0.00031

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