BK809_0003576 protein (Diplodia seriata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

BK809_0003576

Ribosome-recycling factor. (189 aa)

Predicted Functional Partners:

BK809_0004737

0.997

BK809_0000951

0.995

BK809_0001371

0.992

BK809_0003945

0.992

BK809_0006038

0.987

BK809_0002267

0.987

BK809_0003030

0.985

RPS0

0.984

BK809_0004567

0.979

BK809_0004067

0.977

Your Current Organism:

Diplodia seriata

NCBI taxonomy Id: 420778
Other names: Botryosphaeria obtusa, CBS 112555, D. seriata

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BK809_0000951	BK809_0001371	A0A1S8B6E0	A0A1S8B8X1	37S ribosomal protein S9, mitochondrial.	Ribosomal protein S16, mitochondrial.	0.999
BK809_0000951	BK809_0002267	A0A1S8B6E0	A0A1S8BF26	37S ribosomal protein S9, mitochondrial.	37S ribosomal protein mrp4, mitochondrial.	0.999
BK809_0000951	BK809_0003030	A0A1S8B6E0	A0A1S8BM43	37S ribosomal protein S9, mitochondrial.	60S ribosomal protein L26-1.	0.999
BK809_0000951	BK809_0003576	A0A1S8B6E0	A0A1S8BG39	37S ribosomal protein S9, mitochondrial.	Ribosome-recycling factor.	0.995
BK809_0000951	BK809_0003945	A0A1S8B6E0	A0A1S8BCU9	37S ribosomal protein S9, mitochondrial.	54S ribosomal protein subunit img1, mitochondrial.	0.999
BK809_0000951	BK809_0004067	A0A1S8B6E0	A0A0G2F3D0	37S ribosomal protein S9, mitochondrial.	54S ribosomal protein L24, mitochondrial.	0.998
BK809_0000951	BK809_0004567	A0A1S8B6E0	A0A1S8B745	37S ribosomal protein S9, mitochondrial.	37S ribosomal protein MRP17, mitochondrial.	0.999
BK809_0000951	BK809_0004737	A0A1S8B6E0	A0A1S8B7M2	37S ribosomal protein S9, mitochondrial.	54S ribosomal protein L8, mitochondrial; Belongs to the bacterial ribosomal protein bL17 family.	0.999
BK809_0000951	BK809_0006038	A0A1S8B6E0	A0A0G2E6G1	37S ribosomal protein S9, mitochondrial.	Putative 60s ribosomal protein l25.	0.999
BK809_0000951	RPS0	A0A1S8B6E0	A0A0G2G337	37S ribosomal protein S9, mitochondrial.	40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	0.994
BK809_0001371	BK809_0000951	A0A1S8B8X1	A0A1S8B6E0	Ribosomal protein S16, mitochondrial.	37S ribosomal protein S9, mitochondrial.	0.999
BK809_0001371	BK809_0002267	A0A1S8B8X1	A0A1S8BF26	Ribosomal protein S16, mitochondrial.	37S ribosomal protein mrp4, mitochondrial.	0.999
BK809_0001371	BK809_0003030	A0A1S8B8X1	A0A1S8BM43	Ribosomal protein S16, mitochondrial.	60S ribosomal protein L26-1.	0.998
BK809_0001371	BK809_0003576	A0A1S8B8X1	A0A1S8BG39	Ribosomal protein S16, mitochondrial.	Ribosome-recycling factor.	0.992
BK809_0001371	BK809_0003945	A0A1S8B8X1	A0A1S8BCU9	Ribosomal protein S16, mitochondrial.	54S ribosomal protein subunit img1, mitochondrial.	0.999
BK809_0001371	BK809_0004067	A0A1S8B8X1	A0A0G2F3D0	Ribosomal protein S16, mitochondrial.	54S ribosomal protein L24, mitochondrial.	0.999
BK809_0001371	BK809_0004567	A0A1S8B8X1	A0A1S8B745	Ribosomal protein S16, mitochondrial.	37S ribosomal protein MRP17, mitochondrial.	0.999
BK809_0001371	BK809_0004737	A0A1S8B8X1	A0A1S8B7M2	Ribosomal protein S16, mitochondrial.	54S ribosomal protein L8, mitochondrial; Belongs to the bacterial ribosomal protein bL17 family.	0.999
BK809_0001371	BK809_0006038	A0A1S8B8X1	A0A0G2E6G1	Ribosomal protein S16, mitochondrial.	Putative 60s ribosomal protein l25.	0.998
BK809_0001371	RPS0	A0A1S8B8X1	A0A0G2G337	Ribosomal protein S16, mitochondrial.	40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	0.994

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Network Stats

number of nodes:

11

number of edges:

25

average node degree:

4.55

avg. local clustering coefficient:

0.864

expected number of edges:

16

PPI enrichment p-value:

0.0281

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006259

DNA metabolic process

6 of 341

1.14

0.82

0.0056

GO:0006289

Nucleotide-excision repair

3 of 40

1.77

0.77

0.0322

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003712

Transcription coregulator activity

4 of 63

1.69

1.33

0.0015

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030894

Replisome

3 of 11

2.33

1.92

0.00023

GO:0016592

Mediator complex

3 of 20

2.07

1.6

0.00075

GO:0005662

DNA replication factor A complex

2 of 2

2.89

1.51

0.0018

GO:0140513

Nuclear protein-containing complex

6 of 587

0.9

0.67

0.0043

GO:0005634

Nucleus

11 of 2090

0.61

0.53

0.00015

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:8509

Mediator complex

3 of 10

2.37

1.7

0.00067

CL:6882

HDR through Single Strand Annealing (SSA), and Endodeoxyribonuclease activity

3 of 13

2.25

1.67

0.00067

CL:6885

DNA replication factor A complex, and DNA recombinase assembly

2 of 5

2.49

1.33

0.0036

CL:6873

DNA replication, and DNA Double-Strand Break Repair

4 of 140

1.35

1.02

0.0031

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03420

Nucleotide excision repair

3 of 72

1.51

0.86

0.0152

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005662

DNA replication factor A complex

2 of 3

2.72

1.18

0.0072

GOCC:0005634

Nucleus

10 of 1209

0.81

0.76

2.99e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0010

Activator

3 of 18

2.11

1.71

0.00048

KW-0539

Nucleus

5 of 289

1.13

0.91

0.0021

KW-0805

Transcription regulation

3 of 82

1.45

0.89

0.0113

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01336

OB-fold nucleic acid binding domain

2 of 7

2.35

0.73

0.0469

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