STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BK809_0005616Histone-lysine N-methyltransferase ASH1L. (536 aa)    
Predicted Functional Partners:
BK809_0004417
Histone-lysine N-methyltransferase, H3 lysine-36 specific; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
   
 
0.935
BK809_0005157
Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.
    
 0.890
BK809_0004894
Histone-lysine N-methyltransferase SET9.
   
 
0.863
BK809_0000684
Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
  
  
0.849
BK809_0005719
SET domain-containing protein 3.
   
 0.847
BK809_0002892
Histone-lysine N-methyltransferase, H3 lysine-9 specific dim-5.
  
  
0.833
BK809_0007360
SET and MYND domain-containing protein.
     
 0.823
BK809_0005615
Uncharacterized protein.
 
      0.806
BK809_0002431
Histone H3.
 
 
 0.759
BK809_0006064
Histone H3-like centromeric protein cse-4.
 
 
 0.759
Your Current Organism:
Diplodia seriata
NCBI taxonomy Id: 420778
Other names: Botryosphaeria obtusa, CBS 112555, D. seriata
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.