BK809_0006032 protein (Diplodia seriata) - STRING interaction network

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

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[Homology]

Score

BK809_0006032

LIN1-like protein. (471 aa)

Predicted Functional Partners:

BK809_0007322

0.980

BK809_0002036

0.939

BK809_0000680

0.926

BK809_0003643

0.917

BK809_0002620

0.916

BK809_0000698

0.915

BK809_0004068

0.894

BK809_0003354

0.854

BK809_0006146

0.796

BK809_0007206

0.745

Your Current Organism:

Diplodia seriata

NCBI taxonomy Id: 420778
Other names: Botryosphaeria obtusa, CBS 112555, D. seriata

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BK809_0000680	BK809_0000698	A0A1S8BC63	A0A1S8BBZ9	Pre-mRNA-splicing ATP-dependent RNA helicase prp28; Belongs to the DEAD box helicase family.	Small nuclear ribonucleoprotein-associated protein B.	0.960
BK809_0000680	BK809_0002036	A0A1S8BC63	A0A0G2FT59	Pre-mRNA-splicing ATP-dependent RNA helicase prp28; Belongs to the DEAD box helicase family.	Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family.	0.978
BK809_0000680	BK809_0002620	A0A1S8BC63	A0A0G2GTK4	Pre-mRNA-splicing ATP-dependent RNA helicase prp28; Belongs to the DEAD box helicase family.	Putative pre-mrna splicing factor prp1.	0.990
BK809_0000680	BK809_0003354	A0A1S8BC63	A0A1S8BFE7	Pre-mRNA-splicing ATP-dependent RNA helicase prp28; Belongs to the DEAD box helicase family.	ATP-dependent DNA helicase MER3.	0.603
BK809_0000680	BK809_0003643	A0A1S8BC63	A0A1S8BGQ5	Pre-mRNA-splicing ATP-dependent RNA helicase prp28; Belongs to the DEAD box helicase family.	Pre-mRNA-processing-splicing factor 8.	0.995
BK809_0000680	BK809_0004068	A0A1S8BC63	A0A1S8BDI7	Pre-mRNA-splicing ATP-dependent RNA helicase prp28; Belongs to the DEAD box helicase family.	U4/U6.U5 tri-snRNP-associated protein 1.	0.970
BK809_0000680	BK809_0006032	A0A1S8BC63	A0A1S8BPD7	Pre-mRNA-splicing ATP-dependent RNA helicase prp28; Belongs to the DEAD box helicase family.	LIN1-like protein.	0.926
BK809_0000680	BK809_0006146	A0A1S8BC63	A0A1S8B2Q0	Pre-mRNA-splicing ATP-dependent RNA helicase prp28; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.780
BK809_0000680	BK809_0007206	A0A1S8BC63	A0A0G2EH93	Pre-mRNA-splicing ATP-dependent RNA helicase prp28; Belongs to the DEAD box helicase family.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.976
BK809_0000680	BK809_0007322	A0A1S8BC63	A0A1S8BIE6	Pre-mRNA-splicing ATP-dependent RNA helicase prp28; Belongs to the DEAD box helicase family.	Pre-mRNA-splicing factor brr2.	0.979
BK809_0000698	BK809_0000680	A0A1S8BBZ9	A0A1S8BC63	Small nuclear ribonucleoprotein-associated protein B.	Pre-mRNA-splicing ATP-dependent RNA helicase prp28; Belongs to the DEAD box helicase family.	0.960
BK809_0000698	BK809_0002036	A0A1S8BBZ9	A0A0G2FT59	Small nuclear ribonucleoprotein-associated protein B.	Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family.	0.964
BK809_0000698	BK809_0002620	A0A1S8BBZ9	A0A0G2GTK4	Small nuclear ribonucleoprotein-associated protein B.	Putative pre-mrna splicing factor prp1.	0.990
BK809_0000698	BK809_0003354	A0A1S8BBZ9	A0A1S8BFE7	Small nuclear ribonucleoprotein-associated protein B.	ATP-dependent DNA helicase MER3.	0.945
BK809_0000698	BK809_0003643	A0A1S8BBZ9	A0A1S8BGQ5	Small nuclear ribonucleoprotein-associated protein B.	Pre-mRNA-processing-splicing factor 8.	0.992
BK809_0000698	BK809_0004068	A0A1S8BBZ9	A0A1S8BDI7	Small nuclear ribonucleoprotein-associated protein B.	U4/U6.U5 tri-snRNP-associated protein 1.	0.977
BK809_0000698	BK809_0006032	A0A1S8BBZ9	A0A1S8BPD7	Small nuclear ribonucleoprotein-associated protein B.	LIN1-like protein.	0.915
BK809_0000698	BK809_0006146	A0A1S8BBZ9	A0A1S8B2Q0	Small nuclear ribonucleoprotein-associated protein B.	Uncharacterized protein.	0.633
BK809_0000698	BK809_0007206	A0A1S8BBZ9	A0A0G2EH93	Small nuclear ribonucleoprotein-associated protein B.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.998
BK809_0000698	BK809_0007322	A0A1S8BBZ9	A0A1S8BIE6	Small nuclear ribonucleoprotein-associated protein B.	Pre-mRNA-splicing factor brr2.	0.992

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Network Stats

number of nodes:

11

number of edges:

39

average node degree:

7.09

avg. local clustering coefficient:

0.95

expected number of edges:

25

PPI enrichment p-value:

0.00477

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

7 of 98

1.44

1.91

1.55e-06

GO:0010467

Gene expression

8 of 203

1.18

1.43

1.55e-06

GO:0009059

Macromolecule biosynthetic process

8 of 233

1.12

1.3

2.53e-06

GO:0044271

Cellular nitrogen compound biosynthetic process

8 of 314

0.99

1.02

1.67e-05

GO:0009987

Cellular process

10 of 1616

0.37

0.27

0.0284

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

6 of 54

1.63

2.24

1.49e-06

GO:0019843

rRNA binding

4 of 40

1.58

1.42

0.00057

GO:0000049

tRNA binding

3 of 20

1.76

1.3

0.0020

GO:0003723

RNA binding

5 of 98

1.29

1.17

0.00057

GO:0005525

GTP binding

3 of 32

1.55

1.02

0.0062

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

6 of 62

1.57

2.23

6.25e-07

GO:0044391

Ribosomal subunit

3 of 13

1.94

1.91

0.00012

GO:0015935

Small ribosomal subunit

2 of 6

2.1

1.39

0.0022

GO:0032991

Protein-containing complex

4 of 119

1.11

0.88

0.0022

GO:0005622

Intracellular anatomical structure

8 of 885

0.54

0.41

0.0036

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:300

Ribosome

8 of 61

1.7

3.23

4.70e-10

CL:304

Ribosome

7 of 52

1.71

3.07

3.34e-09

CL:306

rRNA-binding

4 of 27

1.75

1.93

4.70e-05

CL:366

Ribosome

3 of 13

1.94

1.67

0.00042

CL:368

Structural constituent of ribosome

2 of 6

2.1

1.1

0.0082

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

sgn03010

Ribosome

6 of 55

1.62

2.4

3.23e-07

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009507

Chloroplast

3 of 25

1.66

0.98

0.0100

GOCC:0005840

Ribosome

3 of 39

1.47

0.91

0.0100

GOCC:0043229

Intracellular organelle

6 of 288

0.9

0.61

0.0100

GOCC:0005622

Intracellular

9 of 959

0.55

0.39

0.0100

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

6 of 58

1.6

2.26

7.88e-07

KW-0699

rRNA-binding

3 of 37

1.49

0.96

0.0077

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03144

Elongation factor Tu domain 2

2 of 4

2.28

0.78

0.0376

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR005225

Small GTP-binding protein domain

3 of 10

2.06

1.25

0.0041

IPR035647

EF-G domain III/V-like

2 of 4

2.28

0.8

0.0340

IPR031157

Tr-type G domain, conserved site

2 of 4

2.28

0.8

0.0340

IPR004161

Translation elongation factor EFTu-like, domain 2

2 of 4

2.28

0.8

0.0340

IPR000640

Elongation factor EFG, domain V-like

2 of 3

2.41

0.8

0.0340

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00838

Elongation factor G C-terminus

2 of 3

2.41

1.2

0.0061

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