Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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LCGL_0065Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (575 aa)    
Predicted Functional Partners:
LCGL_0064
Phosphocarrier protein Hpr.
 
 0.999
LCGL_1195
Conserved hypothetical protein.
 
 0.988
LCGL_1046
N-acetylglucosamine-specific PTS system IIABC components.
 
 0.947
LCGL_0578
Sucrose-specific PTS system IIBC components.
 
 0.939
LCGL_1667
Beta-glucoside-specific PTS system IIABC components.
 
 0.935
LCGL_0590
Truncated fructose-specific PTS system IIABC components.
 
  
 0.913
LCGL_0426
Fructose-specific PTS system enzyme IIABC components.
 
  
 0.898
LCGL_0591
Truncated fructose-specific PTS system IIABC components.
 
  
 0.877
hprK
Hpr kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon s [...]
 
   
 0.842
LCGL_0622
Maltose and glucose-specific PTS system IIABC components.
  
 0.753
Your Current Organism:
Lactococcus garvieae
NCBI taxonomy Id: 420890
Other names: L. garvieae Lg2, Lactococcus garvieae Lg2, Lactococcus garvieae str. Lg2, Lactococcus garvieae strain Lg2
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