Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LCGL_0146Putative acyltransferase. (611 aa)    
Predicted Functional Partners:
LCGL_0437
Sugar transferase EpsD.
     
 0.683
rpmG-2
50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
       0.639
LCGL_0148
Preprotein translocase subunit SecE; Belongs to the SecE/SEC61-gamma family.
       0.636
LCGL_0145
Penicillin-binding protein 2a.
  
  
 0.500
LCGL_1248
Conserved hypothetical protein.
      
 0.476
dltA
D-alanine activating enzyme; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP [...]
  
   
 0.445
nusG
Transcription antitermination protein; Participates in transcription elongation, termination and antitermination.
       0.443
LCGL_0623
Aminotransferase.
      
 0.435
LCGL_0150
Multidrug efflux pump.
       0.410
ruvB
DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
  
    0.408
Your Current Organism:
Lactococcus garvieae
NCBI taxonomy Id: 420890
Other names: L. garvieae Lg2, Lactococcus garvieae Lg2, Lactococcus garvieae str. Lg2, Lactococcus garvieae strain Lg2
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