Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LCGL_0690Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family. (318 aa)    
Predicted Functional Partners:
LCGL_0505
Mannose-specific PTS system IIAB components.
 
  
 0.962
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
 
 
 0.962
glmS
Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.934
nagB
glucosamine-6-P isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
     
 0.934
LCGL_0504
Mannose-specific PTS system IIC component.
 
  
  0.931
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.928
LCGL_0503
Mannose-specific PTS system IID component.
 
  
  0.924
mtlD
Mannitol 1-phosphate 5-dehydrogenase.
    
 0.914
fbp
Fructose-bisphosphatase.
     
 0.904
LCGL_0426
Fructose-specific PTS system enzyme IIABC components.
  
  
 0.824
Your Current Organism:
Lactococcus garvieae
NCBI taxonomy Id: 420890
Other names: L. garvieae Lg2, Lactococcus garvieae Lg2, Lactococcus garvieae str. Lg2, Lactococcus garvieae strain Lg2
Server load: low (12%) [HD]