Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LCGL_1036Acetolactate synthase; Belongs to the TPP enzyme family. (555 aa)    
Predicted Functional Partners:
LCGL_1068
Alpha-acetolactate decarboxylase.
 
 
 0.992
LCGL_0841
Alpha-acetolactate decarboxylase.
 
 
 0.986
LCGL_0303
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.985
LCGL_1832
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
 
 0.961
LCGL_0355
Formate acetyltransferase.
     
 0.925
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.858
LCGL_0416
L-2-hydroxyisocaproate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.858
ldh-2
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.858
LCGL_0962
Pyruvate oxidase; Belongs to the TPP enzyme family.
  
  
 
0.850
LCGL_1336
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.843
Your Current Organism:
Lactococcus garvieae
NCBI taxonomy Id: 420890
Other names: L. garvieae Lg2, Lactococcus garvieae Lg2, Lactococcus garvieae str. Lg2, Lactococcus garvieae strain Lg2
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