Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LCGL_1209Glycerophosphodiester phosphodiesterase. (614 aa)    
Predicted Functional Partners:
LCGL_0034
Glycerophosphodiester phosphodiesterase.
 
  
 
0.906
LCGL_1883
Alcohol-acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.732
LCGL_0810
Glycerol-3-phosphate dehydrogenase.
  
 0.694
dltC
D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
 
   
 0.651
LCGL_1080
D-alanine transfer protein.
  
     0.614
LCGL_1208
ABC transporter ATP-binding component.
  
    0.555
LCGL_1709
CDP-diacylglycerol-phosphate phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
 
 0.550
dltA
D-alanine activating enzyme; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP [...]
  
  
 0.519
LCGL_0496
Phosphate ABC transporter permease component.
  
  
 0.511
LCGL_1082
Conserved hypothetical protein; Could be involved in the transport of activated D-alanine through the membrane.
  
    0.492
Your Current Organism:
Lactococcus garvieae
NCBI taxonomy Id: 420890
Other names: L. garvieae Lg2, Lactococcus garvieae Lg2, Lactococcus garvieae str. Lg2, Lactococcus garvieae strain Lg2
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