Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LCGL_1371Conserved hypothetical protein. (80 aa)    
Predicted Functional Partners:
LCGL_1369
Hypothetical protein.
  
  
 0.721
LCGL_1370
Conserved hypothetical protein.
       0.668
LCGL_0330
N-acetylmuramidase.
  
  
 0.453
LCGL_1372
Conserved hypothetical protein.
       0.437
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
      
 0.433
LCGL_1281
30S ribosomal protein S1.
  
  
 0.423
LCGL_1367
ABC transporter permease component.
       0.421
LCGL_1368
ABC transporter ATP-binding component.
       0.421
ftsE
Cell-division ATP-binding protein; Part of the ABC transporter FtsEX involved in cellular division.
  
  
 0.414
LCGL_1373
Cell division protein; Belongs to the SEDS family.
  
  
 0.413
Your Current Organism:
Lactococcus garvieae
NCBI taxonomy Id: 420890
Other names: L. garvieae Lg2, Lactococcus garvieae Lg2, Lactococcus garvieae str. Lg2, Lactococcus garvieae strain Lg2
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