Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LCGL_1932Cell shape determining protein MreC; Involved in formation and maintenance of cell shape. (285 aa)    
Predicted Functional Partners:
LCGL_1931
Cell shape determining protein MreD.
  
 
 0.997
LCGL_0208
Penicillin-binding protein 2B.
 
 
 0.963
LCGL_1373
Cell division protein; Belongs to the SEDS family.
 
  
 0.900
LCGL_0611
Penicillin-binding protein 2X.
 
 
 0.894
LCGL_0556
Cell division initiation protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
 
 
 0.835
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
 
  
 0.808
LCGL_0359
Cell division protein FtsW; Belongs to the SEDS family.
 
  
 0.794
LCGL_0145
Penicillin-binding protein 2a.
  
 
 0.793
ftsA
Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
 
  
 0.787
LCGL_1019
DNA repair protein; Belongs to the UPF0758 family.
  
  
 0.777
Your Current Organism:
Lactococcus garvieae
NCBI taxonomy Id: 420890
Other names: L. garvieae Lg2, Lactococcus garvieae Lg2, Lactococcus garvieae str. Lg2, Lactococcus garvieae strain Lg2
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.