STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHH72611.12-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. (138 aa)    
Predicted Functional Partners:
SHH43533.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 
 0.998
SHH73610.1
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.996
folE
GTP cyclohydrolase I.
 
  
 0.970
SHH07620.1
Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
 
 
 0.798
ribB
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 0.759
SHH45130.1
Dinuclear metal center protein, YbgI/SA1388 family; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
    
  0.734
SHH72636.1
OmpA-OmpF porin, OOP family.
       0.722
SHH72592.1
Protease-4.
       0.605
SHH45511.1
XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.577
SHH72668.1
OmpA-OmpF porin, OOP family.
       0.571
Your Current Organism:
Chryseobacterium oranimense
NCBI taxonomy Id: 421058
Other names: C. oranimense, Chryseobacterium oranimense Hantsis-Zacharov et al. 2008, DSM 19055, LMG 24030, LMG:24030, strain H8
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