node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEQ03873.1 | SEQ24099.1 | SAMN04488097_1105 | SAMN04488097_1785 | Allosteric NADP-dependent malic enzyme. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.517 |
SEQ03873.1 | cobB | SAMN04488097_1105 | SAMN04488097_3153 | Allosteric NADP-dependent malic enzyme. | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | 0.410 |
SEQ03873.1 | metG | SAMN04488097_1105 | SAMN04488097_2258 | Allosteric NADP-dependent malic enzyme. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.601 |
SEQ03873.1 | ppnK | SAMN04488097_1105 | SAMN04488097_1784 | Allosteric NADP-dependent malic enzyme. | NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.706 |
SEQ14191.1 | SEQ45723.1 | SAMN04488097_1454 | SAMN04488097_2115 | NUDIX domain-containing protein. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.915 |
SEQ14191.1 | cobB | SAMN04488097_1454 | SAMN04488097_3153 | NUDIX domain-containing protein. | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | 0.921 |
SEQ14191.1 | nadD | SAMN04488097_1454 | SAMN04488097_1433 | NUDIX domain-containing protein. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.915 |
SEQ14191.1 | ppnK | SAMN04488097_1454 | SAMN04488097_1784 | NUDIX domain-containing protein. | NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.915 |
SEQ24035.1 | SEQ24099.1 | SAMN04488097_1783 | SAMN04488097_1785 | Hypothetical protein. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.530 |
SEQ24035.1 | ppnK | SAMN04488097_1783 | SAMN04488097_1784 | Hypothetical protein. | NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.837 |
SEQ24099.1 | SEQ03873.1 | SAMN04488097_1785 | SAMN04488097_1105 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Allosteric NADP-dependent malic enzyme. | 0.517 |
SEQ24099.1 | SEQ24035.1 | SAMN04488097_1785 | SAMN04488097_1783 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Hypothetical protein. | 0.530 |
SEQ24099.1 | ppnK | SAMN04488097_1785 | SAMN04488097_1784 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.532 |
SEQ45723.1 | SEQ14191.1 | SAMN04488097_2115 | SAMN04488097_1454 | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | NUDIX domain-containing protein. | 0.915 |
SEQ45723.1 | cobB | SAMN04488097_2115 | SAMN04488097_3153 | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | 0.927 |
SEQ45723.1 | nadD | SAMN04488097_2115 | SAMN04488097_1433 | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.968 |
SEQ45723.1 | ppnK | SAMN04488097_2115 | SAMN04488097_1784 | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.946 |
SEQ55038.1 | metG | SAMN04488097_2448 | SAMN04488097_2258 | Geranylgeranyl diphosphate synthase, type II; Belongs to the FPP/GGPP synthase family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.562 |
SEQ55038.1 | ppnK | SAMN04488097_2448 | SAMN04488097_1784 | Geranylgeranyl diphosphate synthase, type II; Belongs to the FPP/GGPP synthase family. | NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.509 |
cobB | SEQ03873.1 | SAMN04488097_3153 | SAMN04488097_1105 | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | Allosteric NADP-dependent malic enzyme. | 0.410 |