STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTMF_LOCUS258Exonuclease domain-containing protein. (885 aa)    
Predicted Functional Partners:
PAN3
PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]
    
 0.973
A0A0R3R4S1
Exonuclease domain-containing protein.
  
 0.942
A0A0R3R071
PCNA_C domain-containing protein.
  
 0.934
BTMF_LOCUS6409
Uncharacterized protein.
     
0.840
BTMF_LOCUS7148
Uncharacterized protein.
  
 
 0.808
A0A0R3Q741
HRDC domain-containing protein.
  
 0.798
A0A0R3QXM8
Uncharacterized protein.
    
 0.796
A0A0R3RCZ8
Uncharacterized protein.
    
 0.796
BTMF_LOCUS7594
FHA domain-containing protein; Belongs to the eukaryotic ribosomal protein eL42 family.
    
 0.780
BTMF_LOCUS1465
Uncharacterized protein.
   
 0.774
Your Current Organism:
Brugia timori
NCBI taxonomy Id: 42155
Other names: B. timori
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.