STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTMF_LOCUS6459Uncharacterized protein. (667 aa)    
Predicted Functional Partners:
BTMF_LOCUS5865
Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
      
 0.658
A0A0R3QY60
Uncharacterized protein.
   
  
 0.546
BTMF_LOCUS360
PINc domain-containing protein.
      
 0.485
A0A0R3R6X2
Uncharacterized protein.
    
   0.469
A0A0R3RBK9
Uncharacterized protein.
    
   0.465
BTMF_LOCUS6467
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
      
 0.461
BTMF_LOCUS8882
J domain-containing protein.
    
   0.457
A0A0R3R348
Sm domain-containing protein; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.
    
   0.451
BTMF_LOCUS9358
Uncharacterized protein.
   
  
 0.447
A0A0R3RBB5
Uncharacterized protein.
    
   0.445
Your Current Organism:
Brugia timori
NCBI taxonomy Id: 42155
Other names: B. timori
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.