STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NLS_LOCUS2600Uncharacterized protein; Belongs to the mannose-6-phosphate isomerase type 1 family. (493 aa)    
Predicted Functional Partners:
NLS_LOCUS3209
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.980
NLS_LOCUS4552
Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.
  
 
 0.970
NLS_LOCUS5681
Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
    
 0.951
NLS_LOCUS1765
Uncharacterized protein.
  
 
 0.942
NLS_LOCUS4776
Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.
  
 
 0.941
NLS_LOCUS5156
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
     
 0.932
NLS_LOCUS6651
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
    
 0.929
NLS_LOCUS5653
TRANSKETOLASE_1 domain-containing protein.
  
 
 0.923
NLS_LOCUS7383
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.
   
 
 0.921
NLS_LOCUS5953
Uncharacterized protein.
    
 0.912
Your Current Organism:
Litomosoides sigmodontis
NCBI taxonomy Id: 42156
Other names: L. sigmodontis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.