STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NLS_LOCUS95622-Hacid_dh_C domain-containing protein. (818 aa)    
Predicted Functional Partners:
NLS_LOCUS1042
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.942
NLS_LOCUS117
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.912
NLS_LOCUS5564
Uncharacterized protein.
  
 0.894
NLS_LOCUS6777
Uncharacterized protein.
  
 0.888
NLS_LOCUS7272
PALP domain-containing protein.
  
 0.883
NLS_LOCUS8533
DAO domain-containing protein.
    
 0.873
NLS_LOCUS8707
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
    
 0.870
NLS_LOCUS2719
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
   
 
 0.867
NLS_LOCUS9161
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.856
NLS_LOCUS8811
Uncharacterized protein; Belongs to the TPP enzyme family.
  
 
 0.847
Your Current Organism:
Litomosoides sigmodontis
NCBI taxonomy Id: 42156
Other names: L. sigmodontis
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