NOO_LOCUS5327 protein (Onchocerca ochengi) - STRING interaction network

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Score

NOO_LOCUS5327

POLAc domain-containing protein. (1155 aa)

Predicted Functional Partners:

NOO_LOCUS276

0.863

FEN1

0.817

NOO_LOCUS6443

0.809

NOO_LOCUS2175

0.795

NOO_LOCUS47

0.778

NOO_LOCUS2613

0.768

NOO_LOCUS2678

0.765

NOO_LOCUS8522

0.759

NOO_LOCUS7034

0.753

NOO_LOCUS5814

0.732

Your Current Organism:

Onchocerca ochengi

NCBI taxonomy Id: 42157
Other names: O. ochengi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FEN1	NOO_LOCUS2175	A0A182E1Q8	A0A182E2H4	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein; Belongs to the MRE11/RAD32 family.	0.995
FEN1	NOO_LOCUS2613	A0A182E1Q8	A0A182E3Q4	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.801
FEN1	NOO_LOCUS276	A0A182E1Q8	A0A182DXA2	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.612
FEN1	NOO_LOCUS47	A0A182E1Q8	A0A182DWN0	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	FANCI_HD2 domain-containing protein.	0.426
FEN1	NOO_LOCUS5327	A0A182E1Q8	A0A182EB95	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	POLAc domain-containing protein.	0.817
FEN1	NOO_LOCUS5814	A0A182E1Q8	A0A182ECM0	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.817
FEN1	NOO_LOCUS6443	A0A182E1Q8	A0A182EED8	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	ERCC4 domain-containing protein.	0.939
FEN1	NOO_LOCUS7034	A0A182E1Q8	A0A182EG15	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	SAE2 domain-containing protein.	0.914
FEN1	NOO_LOCUS8522	A0A182E1Q8	A0A182EK87	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	ERCC4 domain-containing protein.	0.969
NOO_LOCUS2175	FEN1	A0A182E2H4	A0A182E1Q8	Uncharacterized protein; Belongs to the MRE11/RAD32 family.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.995
NOO_LOCUS2175	NOO_LOCUS2613	A0A182E2H4	A0A182E3Q4	Uncharacterized protein; Belongs to the MRE11/RAD32 family.	Uncharacterized protein.	0.993
NOO_LOCUS2175	NOO_LOCUS276	A0A182E2H4	A0A182DXA2	Uncharacterized protein; Belongs to the MRE11/RAD32 family.	Uncharacterized protein.	0.654
NOO_LOCUS2175	NOO_LOCUS47	A0A182E2H4	A0A182DWN0	Uncharacterized protein; Belongs to the MRE11/RAD32 family.	FANCI_HD2 domain-containing protein.	0.462
NOO_LOCUS2175	NOO_LOCUS5327	A0A182E2H4	A0A182EB95	Uncharacterized protein; Belongs to the MRE11/RAD32 family.	POLAc domain-containing protein.	0.795
NOO_LOCUS2175	NOO_LOCUS5814	A0A182E2H4	A0A182ECM0	Uncharacterized protein; Belongs to the MRE11/RAD32 family.	Uncharacterized protein.	0.795
NOO_LOCUS2175	NOO_LOCUS6443	A0A182E2H4	A0A182EED8	Uncharacterized protein; Belongs to the MRE11/RAD32 family.	ERCC4 domain-containing protein.	0.914
NOO_LOCUS2175	NOO_LOCUS7034	A0A182E2H4	A0A182EG15	Uncharacterized protein; Belongs to the MRE11/RAD32 family.	SAE2 domain-containing protein.	0.993
NOO_LOCUS2175	NOO_LOCUS8522	A0A182E2H4	A0A182EK87	Uncharacterized protein; Belongs to the MRE11/RAD32 family.	ERCC4 domain-containing protein.	0.905
NOO_LOCUS2613	FEN1	A0A182E3Q4	A0A182E1Q8	Uncharacterized protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.801
NOO_LOCUS2613	NOO_LOCUS2175	A0A182E3Q4	A0A182E2H4	Uncharacterized protein.	Uncharacterized protein; Belongs to the MRE11/RAD32 family.	0.993