STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOO_LOCUS5640Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. In the CBC complex, ncbp-2 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp-1 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. (160 aa)    
Predicted Functional Partners:
NOO_LOCUS2525
Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.
   
 0.998
NOO_LOCUS2117
Small nuclear ribonucleoprotein G.
   
 0.997
NOO_LOCUS3060
Uncharacterized protein.
   
 0.995
NOO_LOCUS3199
MIF4G domain-containing protein.
   
 0.995
NOO_LOCUS4082
Small nuclear ribonucleoprotein Sm D2.
   
 0.995
NOO_LOCUS4244
Uncharacterized protein.
   
 0.995
NOO_LOCUS5575
MIF4G domain-containing protein.
   
 0.995
NOO_LOCUS6663
Sm domain-containing protein; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.
   
 0.995
NOO_LOCUS9156
Uncharacterized protein.
   
 0.995
NOO_LOCUS5729
Uncharacterized protein.
    
 0.994
Your Current Organism:
Onchocerca ochengi
NCBI taxonomy Id: 42157
Other names: O. ochengi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.