hmgA protein (Streptomyces acidiscabies) - STRING interaction network

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hmgA

Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (443 aa)

Predicted Functional Partners:

hpd_2

0.998

IQ63_38195

0.991

hpd_1

0.990

IQ63_02100

0.928

yvoA_4

0.876

IQ63_01235

0.827

IQ63_03185

0.787

IQ63_05235

0.787

IQ63_40300

0.787

tetR_7

0.785

Your Current Organism:

Streptomyces acidiscabies

NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IQ63_01235	hmgA	IQ63_01235	IQ63_01220	DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	0.827
IQ63_01235	tetR_7	IQ63_01235	IQ63_01210	DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.748
IQ63_01235	yvoA_4	IQ63_01235	IQ63_01225	DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.827
IQ63_02100	hmgA	IQ63_02100	IQ63_01220	methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	0.928
IQ63_03185	IQ63_05235	IQ63_03185	IQ63_05235	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.604
IQ63_03185	IQ63_40300	IQ63_03185	IQ63_40300	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ureidoglycolate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.613
IQ63_03185	hmgA	IQ63_03185	IQ63_01220	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	0.787
IQ63_05235	IQ63_03185	IQ63_05235	IQ63_03185	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.604
IQ63_05235	hmgA	IQ63_05235	IQ63_01220	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	0.787
IQ63_38195	hmgA	IQ63_38195	IQ63_01220	Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	0.991
IQ63_38195	hpd_1	IQ63_38195	IQ63_11230	Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.444
IQ63_38195	hpd_2	IQ63_38195	IQ63_05645	Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.956
IQ63_40300	IQ63_03185	IQ63_40300	IQ63_03185	Ureidoglycolate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.613
IQ63_40300	hmgA	IQ63_40300	IQ63_01220	Ureidoglycolate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	0.787
hmgA	IQ63_01235	IQ63_01220	IQ63_01235	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.827
hmgA	IQ63_02100	IQ63_01220	IQ63_02100	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.928
hmgA	IQ63_03185	IQ63_01220	IQ63_03185	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.787
hmgA	IQ63_05235	IQ63_01220	IQ63_05235	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.787
hmgA	IQ63_38195	IQ63_01220	IQ63_38195	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.991
hmgA	IQ63_40300	IQ63_01220	IQ63_40300	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	Ureidoglycolate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.787

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