STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppnKInorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (301 aa)    
Predicted Functional Partners:
tlyA
Cytochrome C oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.975
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.948
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.940
cobB_1
NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.915
sthA
Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.895
nudC_2
NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.891
mazG
Nucleoside triphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.820
recN
DNA recombination protein RecN; May be involved in recombinational repair of damaged DNA.
 
  
 0.816
IQ63_01615
Sterol-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.738
kch
Ion channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.709
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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