STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mshD_5GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)    
Predicted Functional Partners:
IQ63_03865
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.837
arc
ATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
  
    0.807
proS_2
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
       0.773
IQ63_30390
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.760
IQ63_02895
Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.713
IQ63_22265
Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.710
IQ63_00050
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.652
IQ63_11480
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.625
rsrA
Anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.615
IQ63_07810
ArsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.607
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.