Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
mscLMechanosensitive ion channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (158 aa)    
Predicted Functional Partners:
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.960
IQ63_36040
Catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.789
IQ63_36045
Catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.789
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
    0.789
IQ63_04080
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.753
mtnP
Purine nucleoside phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.
       0.669
nhaP
Potassium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.655
IQ63_04090
FmdB family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.643
IQ63_04095
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.631
mog
Molybdenum cofactor synthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.562
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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