STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
whiASporulation protein; Involved in cell division and chromosome segregation. (329 aa)    
Predicted Functional Partners:
IQ63_07700
Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.
 
  
 0.966
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
 
 
 0.966
IQ63_07695
glmZ(sRNA)-inactivating NTPase; Displays ATPase and GTPase activities.
 
  
 0.952
whiB_2
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
 
 
 0.949
rbpA_1-2
Membrane protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
  
 
 
 0.948
hrdB_1
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 
 0.918
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.913
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
   0.913
uvrC
Excinuclease ABC subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.900
whmD
Transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
 
 
 0.892
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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