Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IQ63_07995Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)    
Predicted Functional Partners:
ribD2_2
5-amino-6-(5-phosphoribosylamino)uracil reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.772
guaB_2
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.748
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.743
ppgK
Polyphosphate glucokinase; Catalyzes the phosphorylation of glucose using polyphosphate or ATP as the phosphoryl donor; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.720
pgm
Phosphoglucomutase; Catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.706
malP
Glycogen phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.688
hddC_2
Mannose-1-phosphate guanyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.686
rfbF_1
Glucose-1-phosphate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.685
bsr
Biotin transporter BioY; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.673
IQ63_17260
Aldose epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.671
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.