STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clgR_1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa)    
Predicted Functional Partners:
rbpA_1-2
Membrane protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
  
    0.725
IQ63_22185
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.724
sigF_2
RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family.
       0.720
IQ63_10595
Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.706
IQ63_13900
MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.666
pspA_6
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.661
xseB
Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
  
     0.658
IQ63_06740
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.624
nucS
Endonuclease; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
  
     0.618
ssb1
Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.610
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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