Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
afsR_18Regulatory protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (742 aa)    
Predicted Functional Partners:
IQ63_14685
ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.632
IQ63_27930
Regulatory protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.628
IQ63_29565
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.558
IQ63_25875
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.537
IQ63_24470
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.518
IQ63_30405
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.511
IQ63_15630
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.492
IQ63_27175
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.486
sti2
Protease inhibitor protein; Strong inhibitor of bacterial serine proteases such as subtilisin.
  
     0.479
yceD_4
Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.471
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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