STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybdKGlutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (505 aa)    
Predicted Functional Partners:
IQ63_13820
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.739
ggt_2
Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.646
patB
Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.610
ggt_1
Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.564
gshA_2
Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine.
    
  0.555
ndhI
NADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
  0.543
yxeP_2
Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.541
metB_1
Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.495
metB_2
Cystathionine gamma-lyase; Catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.495
IQ63_26605
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.493
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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